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PostSubject: Traumatic brain injury   Traumatic brain injury EmptyWed Jan 05, 2011 9:11 pm

Traumatic brain injury is damage to the brain as the result of an injury.

Traumatic brain injury usually results from a violent blow or jolt to the head that causes the brain to collide with the inside of the skull. An object penetrating the skull, such as a bullet or shattered piece of skull, also can cause traumatic brain injury.

Mild traumatic brain injury may cause temporary dysfunction of brain cells. More serious traumatic brain injury can result in bruising, torn tissues, bleeding and other physical damage to the brain that can result in long-term complications or death.


Traumatic brain injury can have wide-ranging physical and psychological effects. Some signs or symptoms may appear immediately after the traumatic event, while others may appear days or weeks later.

Mild traumatic brain injury
The signs and symptoms of mild traumatic brain injury (concussion) may include:

* Loss of consciousness for a few seconds to a few minutes
* No loss of consciousness, but a state of being dazed, confused or disoriented
* Memory or concentration problems
* Headache
* Dizziness or loss of balance
* Nausea or vomiting
* Sensory problems, such as blurred vision, ringing in the ears or a bad taste in the mouth
* Sensitivity to light or sound
* Mood changes or mood swings
* Feeling depressed or anxious
* Fatigue or drowsiness
* Difficulty sleeping
* Sleeping more than usual

Moderate to severe traumatic brain injuries
Moderate to severe traumatic brain injury can include any of the signs and symptoms of mild injury, as well as the following symptoms that may appear within the first hours to days after a head injury:

* Loss of consciousness from a few minutes to hours
* Profound confusion
* Agitation, combativeness or other unusual behavior
* Slurred speech
* Inability to awaken from sleep
* Weakness or numbness in the extremities
* Loss of coordination
* Loss of bladder control or bowel control
* Persistent headache or headache that worsens
* Repeated vomiting or nausea
* Convulsions or seizures
* Dilation of one or both pupils of the eyes
* Clear fluids draining from the nose or ears

Children's symptoms
Infants and young children with brain injuries may lack the communication skills to report headaches, sensory problems, confusion and similar symptoms. In a child with traumatic brain injury, you may observe:

* Change in nursing or eating habits
* Persistent crying
* Unusual or easy irritability
* Change in ability to pay attention
* Inability to be consoled
* Change in sleep habits
* Sad or depressed mood
* Loss of interest in favorite toys or activities

When to see a doctor
Always see your doctor if you or your child has received a blow to the head. Seek emergency medical care if there are any signs or symptoms of traumatic brain injury following a recent blow or other traumatic injury to the head.

The terms "mild," "moderate" and "severe" are used to describe the effect of the injury on brain function. A "mild" injury to the brain is still a serious injury that requires prompt attention and an accurate diagnosis.


Traumatic brain injury is caused by a blow or other traumatic injury to the head. The degree of damage can depend on several factors including the nature of the event and the force of impact. Injury may include one or more of the following factors:

* Damage to brain cells may be limited to the area directly below the point of impact on the skull.
* A severe blow or jolt can cause multiple points of damage because the brain may bounce back and forth in the skull.
* A severe rotational or spinning jolt can cause the tearing of cellular structures.
* A blast, as from an explosive device, can cause widespread damage.
* An object penetrating the skull can cause severe, irreparable damage to brain cells, blood vessels and protective tissues around the brain.
* Bleeding in or around the brain, swelling, and blood clots can disrupt the oxygen supply to the brain and cause more widespread damage.

Common causes
Common events causing traumatic brain injury include the following:

* Falls. Falling out of bed, slipping in the bath, falling down steps, falling from ladders and related falls are the most common cause of traumatic brain injury overall, particularly in older adults and young children.
* Vehicle-related collisions. Collisions involving cars, motorcycles or bicycles — and pedestrians involved in such accidents — are a common cause of traumatic brain injury, particularly among adults in their early 20s.
* Violence. About 10 percent of traumatic brain injuries are caused by violence, such as gunshot wounds, domestic violence or child abuse. Shaken baby syndrome is traumatic brain injury caused by the violent shaking of an infant that damages brain cells.
* Sports injuries. Traumatic brain injuries may be caused by injuries from a number of sports, including boxing, football, baseball, lacrosse, skateboarding, hockey, and other high-impact or extreme sports.
* Explosive blasts and other combat injuries. Explosive blasts are a common cause of traumatic brain injury in active-duty military personnel. Although the mechanism of damage isn't well understood, many researchers believe that the pressure wave passing through the brain significantly disrupts brain function. Traumatic brain injury also results from penetrating wounds, severe blows to the head with shrapnel or debris, and falls or bodily collisions with objects following a blast.

Risk factors

The people most at risk of traumatic brain injury include:

* Children, especially newborns to 4-year-olds
* Teenagers, especially those 15 to 19 years of age
* Adults over 65


Several complications can occur immediately or soon after a traumatic brain injury. Severe injuries increase the risk of a greater number of complications and more-severe complications.

Altered consciousness
Moderate to severe traumatic brain injury can result in prolonged or permanent changes in a person's state of consciousness, awareness or responsiveness. Different states of consciousness include:

* Coma. A person in a coma is unconscious, unaware of anything and unable to respond to any stimulus. This results from widespread damage to all parts of the brain. After a few days to a few weeks, a person may emerge from a coma or progress to a vegetative state.
* Vegetative state. Widespread damage to the brain can result in a vegetative state. While the person is unaware of his or her surroundings, he or she may groan or have open eyes or reflex responses. It is possible that a vegetative state can become permanent, but often individuals progress to a minimally conscious state.
* Minimally conscious state. A minimally conscious state is a condition of severely altered consciousness but with some evidence of self-awareness or awareness of one's environment. It is often a transitional state from a coma or vegetative condition to greater recovery.
* Locked-in syndrome. A person in a locked-in state is aware of surroundings and awake, but he or she can't move or speak. The person may be able to communicate with eye movement or blinking. This state results from damage limited to the lower brain and brainstem.

Some people with traumatic brain injury will have seizures within the first week. More-serious injuries may result in recurring seizures, called post-traumatic epilepsy.

Skull fractures or penetrating wounds can tear the layers of protective tissues (meninges) that surround the brain, thereby enabling bacteria to enter the brain. An infection of the meninges (meningitis) can be especially dangerous because of its potential to spread to the rest of the nervous system.

Nerve damage
Injuries to the base of the skull can damage nerves that emerge directly from the brain (cranial nerves). Cranial nerve damage may result in:

* Paralysis of facial muscles
* Damage to the nerves responsible for eye movements, which can cause double vision
* Damage to the nerves that provide sense of smell
* Loss of vision
* Loss of facial sensation

Cognitive problems
Most people who have had a significant brain injury will experience changes in their cognitive skills. Traumatic brain injury can result in problems with any of these skills:

* Memory
* Learning
* Reasoning
* Problem solving
* Speed of mental processing
* Judgment
* Attention or concentration
* Multitasking
* Organization
* Decision making
* Beginning or completing tasks

Communication problems
Language and communications problems are common following traumatic brain injuries. These problems can cause frustration, conflict and misunderstanding for people with an injury, as well as family members, friends, care providers and medical personnel. Communication problems may include:

* Difficulty understanding or producing spoken and written language (aphasia)
* Difficulty deciphering nonverbal signals
* Inability to organize thoughts and ideas
* Inability to use the muscles needed to form words (dysarthria)
* Problems with changes in tone, pitch or emphasis to express emotions, attitudes or subtle differences in meaning
* Trouble starting or stopping conversations
* Trouble with turn taking or topic selection
* Trouble reading cues from listeners
* Trouble following conversations

Behavioral changes
People who've experienced brain injury often experience changes in behaviors. These may include:

* Difficulty with self-control
* Lack of awareness of abilities
* Risky behavior
* Inaccurate self-image
* Difficulty in social situations
* Verbal or physical outbursts

Emotional changes
Emotional changes may include:

* Depression
* Anxiety
* Mood swings
* Irritability
* Lack of empathy for others
* Lack of motivation

Sensory problems
Problems involving senses may include:

* Persistent ringing in the ears
* Difficulty recognizing objects
* Impaired hand-eye coordination
* Blind spots or double vision
* A bitter taste or a bad smell
* Persistent tingling, itching or pain
* Trouble with balance or dizziness

Degenerative brain diseases
A traumatic brain injury may increase the risk of diseases that result in the gradual degeneration of brain cells and gradual loss of brain functions. These include:

* Alzheimer's disease, which primarily causes the progressive loss of memory and other thinking skills (dementia)
* Parkinson's disease, which primarily causes the progressive loss of motor skills
* Dementia pugilistica — most often associated with repetitive blows to the head in career boxing — which causes dementia and Parkinson's symptoms

Tests and diagnosis

Because traumatic brain injuries are usually emergencies and because consequences can worsen swiftly without treatment, doctors usually need to assess the situation rapidly.

Glasgow Coma Scale
This 15-point test helps a doctor or other emergency medical personnel assess the initial severity of a brain injury by checking a person's ability to follow directions and move their eyes and limbs. The coherence of speech also provides important clues. Abilities are scored numerically. Higher scores mean milder injuries.

Information about the injury and symptoms
If you observed someone being injured or arrived immediately after an injury, you may be able to provide medical personnel with information that's useful in assessing the injured person's condition. Answers to the following questions may be beneficial in judging the severity of injury:

* How did the injury occur?
* Did the person lose consciousness?
* How long was the person unconscious?
* Did you observe any other changes in alertness, speaking, coordination or other signs of injury?
* Where was the head or other parts of the body struck?
* Can you provide any information about the force of the injury? For example, what hit the person's head, how far did he or she fall, or was the person thrown from a vehicle?
* Was the person's body whipped around or severely jarred?

Imaging tests

* CT scans. Computerized tomography (CT) is a specialized X-ray technology that can produce thin cross-sectional images of the brain. A CT scan can quickly visualize fractures and uncover evidence of bleeding in the brain (hemorrhage), blood clots (hematomas), bruised brain tissue (contusions) and brain tissue swelling.
* MRIs. Magnetic resonance imaging (MRI) uses a magnetic field and radio waves to produce cross-sectional or 3-D images of soft tissues. Doctors rarely use MRIs during emergency assessments of traumatic brain injuries because the procedure takes too long to complete. The device may be used after a person's condition has been stabilized.

Intracranial pressure monitor
Tissue swelling from a traumatic brain injury can increase pressure inside the skull and cause additional damage to the brain. Doctors may insert a probe through the skull to monitor this pressure.

Treatments and drugs

Mild injury
Mild traumatic brain injuries usually require no treatment other than rest and over-the-counter pain relievers to treat a headache. However, a person with a mild traumatic brain injury usually needs to be monitored closely at home and with a follow-up doctor appointment for any persistent, worsening or new symptoms.

Your doctor will advise you on when it's appropriate to resume work, school or recreational activities. He or she is likely to advise a gradual return to normal routines.

Immediate emergency care
Emergency care for moderate to severe traumatic brain injury focuses on making sure the person has an adequate oxygen and blood supply, maintaining blood pressure, and preventing any further injury to the head or neck. People with severe injuries may also have other injuries that need to be addressed.

Additional treatments in the emergency room or intensive care unit of a hospital will focus on minimizing secondary damage due to inflammation, bleeding or reduced oxygen supply to the brain.

Medications to limit secondary damage to the brain immediately after an injury may include the following:

* Diuretics. These drugs reduce the amount of fluid in tissues and increase urine output. Diuretics, given intravenously to people with traumatic brain injury, help reduce pressure inside the brain.
* Anti-seizure drugs. People who've had a moderate to severe traumatic brain injury are at risk of having seizures during the first week after their injury. An anti-seizure drug may be given during the first week to avoid any additional brain damage that might be caused by a seizure. Additional anti-seizure treatments are used only if seizures occur.
* Coma-inducing drugs. Doctors sometimes use drugs to put people into temporary comas because a comatose brain needs less oxygen to function. This is especially helpful if blood vessels, compressed by increased pressure in the brain, are unable to deliver the usual amount of nutrients and oxygen to brain cells.

Emergency surgery may be needed to minimize additional damage to brain tissues. Surgery may be used to address the following problems:

* Removing clotted blood (hematomas). Bleeding outside or within the brain can result in a collection of clotted blood (hematoma) that puts pressure on the brain and damages brain tissues.
* Repairing skull fractures. Surgery may be needed to repair severe skull fractures or to remove pieces of skull in the brain.
* Opening a window in the skull. Surgery may be used to relieve pressure inside the skull by draining accumulated cerebral spinal fluid or creating a window in the skull that provides more room for swollen tissues.

Most people who have had a significant brain injury will require rehabilitation. They may need to relearn basic skills, such as walking or talking. The overall goal is to improve their abilities to function at home and in the community.

Therapy usually begins in the hospital and continues at an inpatient rehabilitation unit, a residential treatment facility or through outpatient services. The type and duration of rehabilitation varies by individual, depending on the severity of the brain injury and what part of the brain was injured. Rehabilitation specialists may include:

* Physiatrist, a medical doctor specializing in rehabilitative medicine, who oversees the entire rehabilitative process
* Occupational therapist who helps you learn, relearn or improve skills to perform everyday activities
* Physical therapist, who helps with mobility and relearning movement patterns, balance and walking
* Speech and language pathologist, who helps you improve communication skills and use assistive communication devices if necessary
* Neuropsychologist or psychiatrist, who helps you manage behaviors or learn coping strategies, provide talk therapy as needed for emotional and psychological well-being, and prescribe psychotherapeutic medication as needed
* Social worker or case manager, who facilitates access to service agencies, assists with care decisions and planning, and facilitates communication among various professionals, care providers and family members
* Rehabilitation nurse, who provides ongoing rehabilitation care and services and who helps with discharge planning from the hospital or rehabilitation facility
* Traumatic brain injury nurse specialist, who helps coordinate care and educates families about the injury and recovery process
* Recreational therapist, who helps you explore and participate in leisure activities
* Vocational counselor, who assesses your ability to return to work, appropriate vocational opportunities and provides resources for addressing common challenges in the workplace.


Follow these tips to reduce the risk of brain injury:

* Seatbelts. Always wear a seat belt in a motor vehicle. Small children should always sit in the back seat of a car and be secured in child safety seats or booster seats that are appropriate for their size and weight.
* Alcohol and drug use. Never drive under the influence of alcohol or drugs, including prescription medications that can impair your ability to drive.
* Firearms. Store firearms, unloaded, in a locked cabinet or safe. Store bullets in a separate location.
* Helmets. Wear a helmet while riding a bicycle, skateboard, motorcycle, snowmobile or all-terrain vehicle. Also wear appropriate head protection when you bat or run bases, ski, skate, ride a horse, or play a contact sport.

Preventing falls
The following tips can help older adults avoid falls around the house:

* Install handrails in bathrooms
* Put a nonslip mat in the bathtub or shower
* Remove area rugs
* Install handrails on both sides of staircases
* Improve lighting in the home
* Keep stairs and floors clear of clutter
* Get regular vision checkups
* Get regular exercise

Preventing head injuries in children
The following tips can help children avoid head injuries:

* Install safety gates at the top of stairs
* Install child-height handrails on staircases
* Keep stairs clear of clutter
* Install window guards to prevent falls
* Put a nonslip mat in the bathtub or shower
* Use playgrounds that have shock-absorbing materials on the ground
* Don't let children play on fire escapes or balconies

Coping and support

A number of strategies can help a person with traumatic brain injury cope with complications that affect everyday activities, communication and interpersonal relationships. Depending on the severity of injury, a family caregiver or friend may need to help implement the following strategies:

* Join a support group. Talk to your doctor or rehabilitation therapist about a support group that can help you talk about issues related to your injury, learn new coping strategies and get emotional support.
* Write things down. Keep a record of important events, people's names, tasks or other things that are difficult to remember.
* Follow a routine. Keep a consistent schedule, keep things in designated places to avoid confusion and take the same routes when going to frequently visited destinations.
* Take breaks. Make arrangements at work or school to take breaks as needed.
* Alter work expectations or tasks. Appropriate changes at work or school may include having instructions read to you, allowing more time to complete tasks or breaking down tasks into smaller steps.
* Avoid distractions. Minimize distractions such as loud background noise from a television or radio.
* Stay focused. Work on one task at a time.
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